Principal Investigator
My PhD thesis has focused primarily on elucidating the mechanisms by which systemic inflammation promotes tumor progression in patients with lung and esophageal malignacies. In particular, this work has contributed greatly to the understanding of the role of neutrophil extracellular traps in circulating tumor cell sequestration and tumor progression. This work represents a completely novel process and an exciting potential avenue for therapeutic intervention in the future. Most notably, the publicatons arising as a result of his doctoral thesis (Journal of Clinical Investigation – August 2013) have been widely reported in the global lay media including National Public Radio, Australian Broadcasting Corporation, and Radio Canada.
Jonathan Cools-Lartigue
MD, PhD
AWARDS
Herbert S. Lang Award in Oncology and Surgery (2018)
Phil Gold Discovery of CEA Award (2018)
Canadian Institutes of Health Research grant holder (2014-19)
“Investigating the Role of Neutrophil Extracellular Traps in Cancer Metastasis”
Canadian Society for Clinical Investigation Resident Research Prize (2014)
“Neutrophil Extracellular traps Sequester Circulating Tumor Cells and Promote the Development of Metastasis”
Québec Science (2013) - “Top 10 Discoveries of the Year
"Neutrophil Extracellular Traps Sequester Circulating Tumor Cells and Promote Metastasis”
This project has received significant attention from the press at provincial, national and international levels.
Canadian Institutes of Health Research (2013): Institute of Cancer Research Publication Prize
Leadership Award (2013): McGill University Division of General Surgery for recognition in a leadership role.
Fraser Gurd Annual Resident Research day (2013): 1st Prize
Neutrophil Extracellular Traps Bind Circulating Tumor Cells via β1 Integrin Mediated Interactions
L.D. McLean Annual Resident Research Day (2013): 1st Prize
Neutrophil Extracellular Traps Bind Circulating Tumor Cells via β1 Integrin Mediated Interactions
Fraser Gurd Annual Resident Research day (2012): 1st Prize
Neutrophil extracellular traps sequester circulating tumor cells and promote the development of metastasis
Stikeman Cardiothoracic Research Prize (2012): Best basic research presentation 1st Prize
Neutrophil extracellular traps sequester circulating tumor cells and promote the development of metastasis
Cancer Axis Research Prize (2012): 1st Prize
Neutrophil extracellular traps sequester circulating tumor cells and promote the development of metastasis
Recipient of the Julius Gordon Traveling Grant (2012)
Neutrophil extracellular traps sequester circulating tumor cells and promote the development of metastasis
Canadian Association of General Surgeons 2011
Acute Bacterial Pneumonia Promotes Cancer Metastasis Through Toll Like Receptors
PRESENTATIONS
Survival Rates in Patients with N3 Esophageal Adenocarcinoma Treated with Neoadjuvant Chemotherapy and Esophagectomy with En-Bloc Lymphadenectomy.
Central Surgical Association, 73rd Annual Meeting, March 10-12, 2016, Montreal, Canada
Survival Rates in Patients with N3 Esophageal Adenocarcinoma Treated with Neoadjuvant Chemotherapy and Esophagectomy with en-bloc Lymphadenectomy.
Canadian Surgical Forum, Sept. 19, 2015, Quebec City, Canada
Extent of Lymph Node Involvement after Esophagectomy with Extended Lymphadenectomy for Esophageal Adenocarcinoma Predicts Recurrence: A Large North American Cohort Study.
Society for the Surgery of the Alimentary Tract – Annual Meeting May 19, 2015, Washington, DC
Want to join the Thoracic Surgery & Upper GI Cancer Lab?
Contact Ms. Betty Giannias
Email
514-934-1934 ext. 76102