Principal Investigator

Lorenzo Ferri is the David S. Mulder Chair in Surgery, a clinical scientist in the Departments of Surgery and Oncology specializing in the management of complex malignancies of the foregut, and heads the McGill University Program in Upper GI Cancer. Through this, he has spearheaded numerous initiatives designed to improve outcomes in gastric and esophageal surgery through carefully coordinated basic, translational, and clinical scientific research, and patient care. He established the McGill University Foregut Malignancy Research Group, a multidisciplinary collection of researchers and clinicians with the objective of identifying and executing research ideas in the field of gastric and esophageal cancer.

  Dr Ferri is an independent investigator with active basic science, translational and clinical research programs, all concentrated primarily on malignancies of the chest and foregut.

 

Dr Ferri has initiated numerous clinical programs and studies for esophageal cancer including: Novel combination chemotherapy regimens for neoadjuvant treatment of adenocarcinoma; Optimizing the palliation of metastatic disease; and extensive work into the investigation and optimization of outcomes after esophageal surgery.

 

He is the first physician in Canada to introduce a novel technique of removing early cancers of the esophagus and stomach through endoscopic means (Endoscopic Submucosal Dissection), and has been invited throughout North America to speak on this method. This clinical work is closely coupled to both translational and fundamental research in the area of cancer-inflammation cross talk.

 

Dr Ferri is the recipient of numerous peer review grants (including the Canadian Institutes of Health Research and Canadian Cancer Society) for his work into the inflammatory basis of cancer metastasis. He has identified the important role of bacterial antigens and host neutrophils in propagating cancer dissemination, thus representing a new paradigm in the metastatic process.

 

One of his most recent discovery highlighting the novel finding implicating Neutrophil Extracellular Traps in the metastatic process (Journal of Clinical Investigation – August 2013) was widely reported in the global lay media including National Public Radio, Australian Broadcasting Corporation, and Radio Canada.

LORENZO FERRI

MD, PhD

AWARDS

2014

 

Canadian Institutes of Health Research

Institute of Cancer Research Publication Prize (Supervisor – Jonathan Cools-Lartigue)

 

LD McLean General Surgery Day McGill University

Award for Best Research Presentation (Supervisor)

 

Canadian Society of Surgical Oncology – Annual Meeting

Award for Best Research Presentation (Supervisor)

 

Canadian Society of Clinical Investigation

Canadian Institutes of Health Research Resident Prize (Supervisor – Jonathan Cools Lartigue)

 

James IVth Association of Surgeons

Travelling Fellow for Canada in 2015

 

 

2013

 

McGill University Division of Experimental Surgery Research Day

Best Oral presentation – First Prize (Supervisor)

 

Canadian Institutes of Health Research

Institute of Cancer Research Publication Prize (Supervisor – Jonathan Spicer)

 

LD McLean General Surgery Day McGill University

Award for Best Research Presentation (Supervisor)

 

Canadian Cancer Society Top Research Stories of 2013
“When your own Blood Cells turn against you”

 

Video for magazine Québec Science - “Top 10 Discoveries of the Year”
Montreal General Hospital – Dec. 5/13

 

PRESENTATIONS

"Tu2017 RISK FACTORS AND IMPACT OF PERIOPERATIVE BLOOD TRANSFUSIONS ON SURGICAL AND ONCOLOGIC OUTCOMES AFTER ESOPHAGO-GASTRECTOMY"

Digestive Disease Week

Virtual Meeting, May 2020

 

"1040 PATIENT REMOTENESS FROM URBAN CENTRE DOES NOT IMPACT GASTRIC CANCER OUTCOMES IN THE CONTEXT OF AN ESTABLISHED CARE CORRIDOR TO A SPECIALIST MULTIDISCIPLINARY CANCER CENTRE"

Digestive Disease Week

Virtual Meeting, May 2020

 

"31 TROP2 IS UPREGULATED IN THE TRANSITION FROM METAPLASIA TO DYSPLASIA IN THE GASTRIC MUCOSAL EPITHELIUM"

Digestive Disease Week

Virtual Meeting, May 2020

 

"306 CURATIVE INTENT THERAPY FOR LOCOREGIONAL RECURRENCE OF ESOPHAGEAL CANCER CAN PROLONG SURVIVAL"

Digestive Disease Week

Virtual Meeting, May 2020

 

"Microsatellite Instability Screening in a Canadian Cohort of Esophageal Adenocarcinomas"

United States Canada Association of Pathologists

Los Angeles, February 28-March 5, 2020

 

"Role of Palliative Surgery in Stage IV Gastric Cancer"

Society of Surgical Oncology

Virtual Meeting, 2020

 

"Synchronous pulmonary and esophageal cancers: Is combined esophagectomy and anatomic lung resection appropriate?"

ASCO GI

San Francisco, January 2020

Want to join the Thoracic Surgery & Upper GI Cancer Lab?

Contact Ms. Betty Giannias
Email
514-934-1934 ext. 76102